top of page

Research

At P-NAS lab we focus on novel ideas pertaining to the synthesis and use of various nanoparticles in healthcare. We believe in the ideology of multidisciplinary collaborations which enables us to integrate newer approaches. Nanotechnology has shown immense potential in tackling problems of modern medicine in recent times, but yet there remains many unanswered questions .........

Publications

images_large_mt4c00635_0007.jpeg

Omeprazole-Loaded Copper Nanoparticles for Mitochondrial Damage Mediated Synergistic Anticancer Activity against Melanoma Cells

ACS Applied Bio Materials (2024)

Kalyani Eswar.....A.K. Rengan*

aanmf6.2024.7.issue-20.largecover.jpg
1-s2.0-S0956566324X00135-cov200h.gif
d4nr90185a_page-0001.jpg
amlcef.2023.5.issue-10.largecover.jpg
Applied materials and interfaces.jpg
Get1_edited_edited.jpg
Applied materials today.jpg
ACS Sust.jpg
Picture2.jpg
Inter J BioMacro.jpg
Biomacromolecules.png
Biomaterial Science and Engineering.jpg
Photo Chem n Bio.jpg
showCoverImage.jpg
Nanoletters.jpg
X15721000.jpg
materials today communication.jpg
001aabm.jpeg
Applied Polymer materials_edited.jpg
Picture3_edited.jpg
Materialia.jpg
X00032670.jpg

Selected Recent Original Research Articles

​

  1. Sri Amruthaa Sankaranarayanan, Rupali Srivastava A.K. Rengan*, Development of Gold coated calcium peroxide nanoparticles for photothermal ferroptosis against skin cancer and C. albicans, Communications Chemistry (2026)

  2. Aseem Setia.....A.K. Rengan*, Self-assembled redox sensitive mixed micelles of paclitaxel: Evaluation on 3D tumor spheroids, lung biodistribution, pharmacokinetics, optical and ultrasound/photoacoustic imaging for lung cancer therapy, International Journal of Pharmaceutics (2025) 125872

  3. Tejaswini Appidi....A.K.Rengan* ,Engineered multifunctional nanoparticles for enhanced radiation therapy: three-in-one approach for cancer treatment, Molecular Cancer (2025) (1), 68

  4. ​​​​​Dasari Srideep, Sajmina Khatun, Chandra Lekha Putta.......A. K. Rengan, Kotagiri Venkata Rao*, Self-assembly induced dual-wavelength active photothermal and photodynamic therapies using a near-infrared triimide dye nanoformulations, Nanoscale (2025)

  5. Karri Trinadha Rao....A.K. Rengan*, Silk-polyurethane composite based flexible electrochemical biosensing platform for pathogen detection, Biosensors and Bioelectronics (2025) 271, 117024

  6. Sunil Venkanna Pogu....A.K. Rengan*, Phage-augmented casein nanocarriers for targeted bioimaging and enhanced combinatorial therapy of triple-negative breast cancer, Nanoscale(2025) 17 (32), 18948-18960

  7. Vikas Sonkar....A.K. Rengan*,A multi-endpoint approach to ecotoxicological assessment of wastewater polluted rivers using zebrafish, Environmental Research (2025), 121996

  8. Karri Trinadha Rao....A.K. Rengan*, Silk-polyurethane composite based flexible electrochemical biosensing platform for pathogen detection, Biosensors and Bioelectronics 271, 117024

  9. Rakesh Kumar Rai....A.K. Rengan*, Selective Sensing of the Fluoride Ion in Water and B16F10 Cells by Naphthoimidazolium Salts, ACS Applied Bio Materials (2025) 8 (8), 6999-7010

  10. Neeraja Revi.....A.K. Rengan*, Acridine Benzimidazolium Derivatives Induced Protective Microglia Polarization and In Silico TDP-43 Interaction─Potential Implications for Amyotrophic  Lateral Sclerosis, ACS Chemical Neuroscience (2025)

  11. Dokkari Nagalaxmi Yadav......A.K. Rengan*, One-pot synthesis of tunable fluorescent polyethylene glycol (PEG) polymer for antimicrobial and anticancer theranostics, MedComm- Biomaterials and Applications (2025) e70004

  12. Rounik Karmakar......A.K. Rengan*, Enhanced wound healing properties by sodium alginate-carboxymethyl cellulose hydrogel enriched with decellularized amniotic membrane,  European Journal of Pharmaceutics and Biopharmaceutics (2025) 114621

  13. Chandra Lekha Putta .......A. K. Rengan*, Baicalein and IR780 Coloaded Liposomes for Antifungal and Anticancer Therapy, ACS Applied Bio Materials (2025) 661 

  14. Rupali Srivastava......A.K. Rengan*, Bioinspired Photoresponsive Algosomes as a Nanocarrier for Combating Cancer and Bacterial Infections, ACS Applied Nano Materials (2024) 24246

  15. S A Sankaranarayanan.....A.K. Rengan*, In situ thermosensitive H2O2/NO self-sufficient hydrogel for photothermal ferroptosis of triple-negative breast cancer, Nanoscale (2024) 18899

  16. Mohammad Sadik Ali......A.K. Rengan*, Multifunctional Nanosystem for Dual Anti-Inflammatory and Antibacterial Photodynamic Therapy in Infectious Diabetic Wounds, ACS Infectious Diseases (2024) 2978

  17. Kalyani Eswar.....A.K. Rengan*, Omeprazole-Loaded Copper Nanoparticles for Mitochondrial Damage Mediated Synergistic Anticancer Activity against Melanoma Cells, ACS Applied Bio Materials (2024) 4795

  18. Monika Pebam...............A.K. Rengan*, Self-assembled IR dye/Mitoxantrone loaded Porphysomes Nanosystem for Enhanced Combinatorial Chemo-Photothermal Cancer Therapy, Colloids and Surfaces B: Biointerfaces​ (2024) 113985

  19. Dheeraj Dehariya...............A.K. Rengan*, Hexagon Gold Nanoring-Mediated Combined Phototherapy for the Treatment of B16 Melanoma Cell Line, ACS Applied Nano Materials​ (2024) 12194

  20. Paloma Patra...............A.K. Rengan*, Cancer cell membrane cloaked fluorescent liposomes loaded with metal-phenolic complex nanoparticles for combinatorial therapy against breast cancer, Applied Materials Today (2024) 102211

  21. Vinod R. Shinde, Ajinkya Madhukar Thanekar,...............A.K. Rengan*, Melanin-Ce6-loaded polydopamine nanoparticles-based enhanced phototherapy for B16 melanoma cancer cells, Nanotechnology (2024) 295101

  22. Tejaswini Appidi...............A.K. Rengan*, A lipo-polymeric hybrid nanosystem with metal enhanced fluorescence for targeted imaging of metastatic breast cancer, Nanotheranostics (2024) 239

  23. Sajmina Khatun...............A.K. Rengan*, 7-Amino-6H-anthra[9,1-cd] Isothiazol-6-one-Casein Nanosystem for Live Cell Staining and Augmenting Therapeutic Effectiveness in Triple Negative Breast Cancer, ACS Applied Nano Materials (2024) 8022

  24. Sajmina Khatun...............A.K. Rengan*, Glutathione - IR 797 coupled Casein Nano-Trojan for augmenting the therapeutic efficacy of camptothecin in highly invasive triple-negative breast cancer, Biomaterials Advances (2024) 159

  25. Mohammad Sadik Ali..............A.K. Rengan*, Accelerating Diabetic Wound Healing by Modulating the Inflammatory Environment using Quercetin-Rosemary Oil Lipid Nanoemulsions with Artificial Intelligence-based Wound Closure Analysis, Advanced Therapeutics  (2023) 034

  26. Gayathri Ravichandran,...............A.K. Rengan*, The Multifaceted Role of Degradable Cobalt Nanoparticles: Dual-Target Starvation and Intracellular Acidification Engendering LC3-Associated Whole-Cell Autophagy, ACS Materials Letters 5 (2023) 2726

  27. Sunil Venkanna Pogu, Dokkari Nagalaxmi Yadav, ...............A.K. Rengan* Copper iodide microhexagons: a potential therapeutic agent for surface microbial infection and melanoma Materials Advances 10 (2023) 1039

  28. Dokkari Nagalaxmi Yadav, Sri Amruthaa, ...............A.K. Rengan* Bioinspired Gold coated Phage Nanosomes for Anti-Microbial and Anti-CancerTheranostics Materials Today Nano  23 (2023) 100348

  29. Sushma Mudigunda, Sri Amruthaa,...........A.K. Rengan*, Ethosomal Nanoformulations for Combinational Photothermal Therapy of Fungal Keratitis Advanced Therapeutics 6 (2023)2200331 

  30. S Khatun, M Pebam, CL Putta, A.K. Rengan*,  Camptothecin loaded Casein nanosystem for turning the therapeutic efficacy against highly metastatic triple-negative breast cancer cells, Biomaterials Science,11 (2023) 2518.

  31. A Prajapati, A Srivastava, ...............A.K. Rengan*, High-Affinity DNA NAnomatrix: A platform technology for synergistics Drug Delivery and Photothermal Therapy, ACS Macro Letters 12 (2023) 255.

  32. SV Mudigunda, DB Pemmaraju, SA Sankaranarayanan, A.K. Rengan*, Bioactive Polymeric Nanoparticles of Moringa oleifera Induced Phyto-Photothermal Sensitization for the Enhanced Therapy of Retinoblastoma, Pharmaceutics 2(2023), 15.

  33. S.B.Alvi, P.S.Rajalakshmi, A.B.Jogdand, B.Nazia, V.Bantal, A.K.Rengan*, Chitosan IR806 dye-based polyelectrolyte complex nanoparticles with mitoxantrone combination for effective chemo-photothermal therapy of metastatic triple-negative breast cancer, International Journal of Biological Macromolecules, 216, (2022),558.

  34. Monika Pebam, Rajalakshmi P.S., Madhusree Gangopadhyay, Shashidhar Thatikonda, and Aravind Kumar Rengan*, Terminalia chebula Polyphenol and Near-Infrared Dye-Loaded Poly(lactic acid) Nanoparticles for Imaging and Photothermal Therapy of Cancer Cells , ACS Applied Bio Materials, 11,(2022) 5333.

  35. Tejaswini Appidi, PS Rajalakshmi, Shubham A Chinchulkar, Arpan Pradhan, Hajera Begum, Veeresh Bantal, Rohit Srivastava, Ganesan Prabusankar, A.K.Rengan*, Plasmon-enhanced fluorescent gold coated novel lipo-polymeric hybrid nanosystem: Synthesis, characterization and application for imaging and photothermal therapy of breast cancer, Nanoscale 14 (2022) , 9112.

  36. V.S.Mudigunda, D.Pemmaraju, S.Paradkar, E.R.Puppala,  B.Gawali, USN Murthy, VGM Naidu, A.K.Rengan*, Multifunctional polymeric nanoparticles for chemo/photo theranostics of retinoblastoma, ACS Biomat.Sci.Engg 8 (2022) 151–160.​

Review Articles

  1. Gangaraju Gedda....A. K. Rengan*, Carbon dots: A promising tool for viral infection treatment, Materials Today Bio (2025), 102091

  2. Rupali Srivastava....A. K. Rengan*, Zebrafish as a versatile model organism: From tanks to treatment, MedComm–Future Medicine (2025)*

  3. Gangaraju Gedda....A. K. Rengan*, Carbon dots: A promising tool for viral infection treatment, Materials Today Bio (2025), 102091

  4. Prakshi Chopra....A. K. Rengan*, Extracellular vesicles in dry eye disease and Sjögren’s syndrome: a systematic review on their diagnostic and therapeutic role, Survey of ophthalmology 70 (3), 499-515

  5. ​​​​Sunny Mukherjee,.....A K Rengan* Advancements in Green Nanoparticle Technology: Focusing on the Treatment of Clinical Phytopathogens, Biomolecules (2024)

  6. Aditya Srivastava, Meet Joshi, A K Rengan* Feeding the future: the role of nanotechnology in tailored nutrition, The Nucleus (2024)

  7. Pramit Kumar Ghosh.......A K Rengan*, Telomerase: a nexus between cancer nanotherapy and circadian rhythm, Biomaterials Science (2024)

  8. Sunjeet Saha.......A K Rengan*, Polyurethane Nanoparticles as Versatile Tools in Nanomedicine: A Review, ACS Applied Nano Materials (2024)

  9. Hima Sree Buddhiraju.........A K Rengan* Advances in Peptide-Decorated Targeted Drug Delivery: Exploring Therapeutic Potential and Nanocarrier Strategies, ACS Applied Bio Materials (2023) 

  10. Nitisha Beniwal..........A K Rengan*, Recent Trends in Bio-nanomaterials and Non-invasive Combinatorial Approaches of Photothermal Therapy against Cancer, Nanotheranostics (2024) 8(2)

  11. Pavani Chowdary, Ananya Padmakumar, A K Rengan Exploring the potential of transethosomes in therapeutic delivery: A comprehensive review MedComm – Biomaterials and Applications 4 (2023) e59

  12. Chandra Lekha Putta .......A. K. Rengan* Melatonin: Avenues in cancer therapy and its nanotechnological advancements MedComm – Biomaterials and Applications 2 (2023) e58

  13. Monika Pebam....... A. K. Rengan* Nano Phyto-Phenols as potential immunomodulators: A review  Food and Humanity 1(2023) 809

  14. Rounik Karmakar....... A. K. Rengan* Attributes of Nanomaterials and Nanotopographies for Improved Bone Tissue Engineering and Regeneration  ACS Applied Bio Materials (2023) 

  15. Ananya Padmakumar, ........, A. K. Rengan* Bacteria-Premised Nanobiopesticides for the Management of Phytopathogens and Pests ACS Agric. Sci. Technol.10(2023)1021

  16. Sadik Ali Mohammad, Arshadul Hak,.......A. K. Rengan* Radiotherapy, photodynamic therapy, and cryoablation‐induced abscopal effect: Challenges and future prospects Cancer Innovation 10(2023)1002

  17. Sunil Venkanna Pogu, Dheeraj Dehariya,..........A. K. Rengan* A review on fabrication, actuation, and application of magnetic force driven, light-driven and DNA nano/microrobots in modern theranostics Molecular System Design and Engineering  4 (2023) 2546

  18. Dheeraj Dehariya, Kalyani Eswar,..............., A. K. Rengan*Recent Advances of Nanobubble-based systems in Cancer Therapeutics: A Review Biomedical Engineering Advances 5 (2023)  100080

  19. K Eswar, S Mukherjee, ......, A.K. Rengan*, Immunomodulatory Natural Polysaccharides: An Overview of the Mechanisms Involved - European Polymer Journal, 188 (2023) 111935.

  20. S Khatun, CL Putta, A Hak, A. K. Rengan*, Immunomodulatory nanosystems: An emerging strategy to combact viral infections, Biomaterials, and Biosystems, 9 (2023) 100073.

  21. A. Hak, M.S. Ali, S.A. Sankarnarayana, Vinod R. Shinde, A. K. Rengan*, Chlorine e6: A Promising Photosensitizer in Photo-Based  Cancer Nanomedicine, ACS Applied Bio Materials 6 (2023) 349.

  22. Sajmina Khatun, Tejaswini Appidi,A. K. Rengan* Casein nanoformulations - Potential biomaterials in Food Bioscience (2022)

  23. SA Chinchulkar, P Patra, D Dehariya, A Yu, AK Rengan, Polydopamine nanocomposites and their biomedical applications: A review, Polymers for Advanced Technologies, 10. (2022)5863.

  24. DN Yadav, MS Ali, AM Thanekar, SV Pogu… A.K.Rengan*, Recent advancements in the design of nanodelivery systems of siRNA for cancer therapy, Mol. Pharmaceutics 19 (2022) 4506.

  25. Pratyusha Sambangi, Subramaniam Gopalakrishnan, Monika Pebam , A.K.Rengan* , Nano-biofertilizers on soil health, chemistry, and microbial community: benefits and risks, Proceedings of the Indian National Science Academy volume 88, pages 357–368 (2022)

  26. NP Koyande, R Srivastava, A Padmakumar, AK Rengan, Advances in Nanotechnology for Cancer Immunoprevention and Immunotherapy: A Review, Vaccines 10 (2022)1727.

  27. P Patra, AK Rengan, Cancer Cell Membrane Cloaked Nanocarriers: A Biomimetic Approach Towards Cancer Theranostics, Materials Today Communications, 10 (2022) ​4289

  28. A. Padmakumar, N. P. Koyande, & A. K. Rengan*, Role of hitchhiking on cancer therapeutics, Advanced Therapeutics 12 (2022) 42.

  29. N. Koyande, M. Gangopadhyay, S. Thatikonda, A. K. Rengan*, The role of gut microbiota in the development of colorectal cancer: a review, International Journal of Colorectal Disease (2022) 37, 1509.

  30. S. Khatun, T. Appidi, A.K. Rengan*, The role played by bacterial infections in the onset and metastasis of cancer, Curr. Res. Microb. Sci. 2 (2021) 100078. 

  31. S.P. Singh, T. Appidi, A.K. Rengan*, Biodegradable/disintegrable nanohybrids for photothermal theranostics, Proc. Indian Natl. Sci. Acad. 87 (2021) 94.

  32. A. Hak, V. Ravasaheb Shinde, A.K. Rengan*, A review of advanced nanoformulations in phototherapy for cancer therapeutics, Photodiagnosis Photodyn. Ther. 33 (2021) 102205. 

  33. A.M. Thanekar, S.A. Sankaranarayanan, A.K. Rengan*, Role of nano-sensitizers in radiation therapy of metastatic tumors, Cancer Treat. Res. Commun. 26 (2021) 100303. 

  34. G. Ravichandran, A.K. Rengan*, Aptamer-mediated nanotheranostics for cancer treatment: A review, ACS Appl. Nano Mater. 3 (2020) 9542 

  35. G. Darabdhara, M.R. Das*, S.P. Singh, A.K. Rengan*, S. Szunerits, R. Boukherroub, Ag and Au nanoparticles/reduced graphene oxide composite materials: Synthesis and application in diagnostics and therapeutics, Adv. Colloid Interface Sci. 271 (2019) 101991. 

  36. P. Yadav, S.P. Singh, A.K. Rengan, A. Shanavas, R. Srivastava*, Gold laced bio-macromolecules for theranostic application, Int. J. Biol. Macromol. 110 (2018) 39.

3-s2.0-C2020002699X-cov200h.gif
9781119617181.cover.gif
978-981-16-2782-8.jfif
Advances in Colloid and interface.jpg
Applied Nanomaterials.jpg
INSA.png
Photo diagnosis and dynamic therapy.jpg
384.jpg
Picture1.tif
1-s2.0-S2666517420X00034-cov200h.jpeg
aabmcb.2023.6.issue-10.largecover.jpg
pat.v33.12_edited.jpg

Book Chapters

  1. Sasvat Sayee Ram Ramesh.....A K Rengan*, Nanomaterial-Based Contrast and Therapeutic Agents, Advancements in Cancer Theranostics (2025)

  2. Jagapathi Rao Maddila....A K Rengan*, , Theranostic polymeric micelles mediated drug delivery, Theranostics Nanomaterials in Drug Delivery (2025), 95-109

  3. Pramit Kumar Ghosh....A K Rengan*,, Advances in theranostic nanocarriers for cancer immunotherapy, Theranostics Nanomaterials in Drug Delivery (2025), 411-429

  4. ​Rounik Karmakar......A K Rengan* Nanostructures using 3D printing, Advances in Nanostructures (2025)

  5. Rupali Srivastava............A.K. Rengan* (2024), Phytonanotechnologies for Addressing Antimicrobial Resistance, Medicinal Plants and Antimicrobial Therapies Springer

  6. Sivasubramanian Murugappan............. A.K. Rengan* (2024), Drug-delivery, Antimicrobial, Anticancerous Applications of Green Synthesized Nanomaterials, Green Synthesis of Nanomaterials: Biological and Environmental Applications Wiley

  7. Anindita Tarafdar..........A.K. Rengan* (2023) X-ray photoelectron spectroscopy for biomedical applications Analytical Techniques for Biomedical Nanotechnology  IOP Publishing

  8. Aditya Srivastava..........A.K. Rengan* (2023) The Evolution of 3D Graphene and Its Derivatives for Theranostic Applications 3D Graphene Springer

  9. Sabeerabi Bonala.......A.K. Rengan* (2023) Nanovectors for theranostic applications Advanced Nanoformulations Academic press

  10. Sankaranarayanan SA........A.K. Rengan* (2023) Albumin-based nanocarriers for therapeutic applications Polymeric Nanosystems  Academic press

  11. Shubham Arunrao Chinchulkar.......A.K. Rengan* (2023) 22 - Gold nanoparticle-based biosensing applications and fundamentals of sensor technology: principles and novel designs Fundamentals of Sensor Technology Elsevier

  12. Shubham A. Chinchulkar, Sankaranarayanan S.A., A.K. Rengan* (2023) Nanobiosensor: Advancement in Disease Diagnostic, Springer.

  13. T. Appidi, S. Mudigunda, A.K. Rengan* (2022) Cellulose Nanocrystals, Springer.

  14. T. Appidi, S. Mudigunda, A.K. Rengan* (2022) Multi-Organs-on-a-Chip in Disease Modelling, Springer.

  15. Sankaranarayanan S.A., Singh S.P., A.K. Rengan*. (2022) Theranostics: Principles, Materials, and Technical Advancements - BioSensing, Theranostics, and Medical Devices, Springer.

  16. J.K.Gangasani, D.B.Pemmaraju, USN Murthy, A.K. Rengan, VGM Naidu* (2022) Chemistry of herbal biomolecules: Herbal Biomolecules in Healthcare Applications, Academic Press

  17. D.B.Pemmaraju, A.Ghosh, J.K.Gangasani, USN Murthy, VGM Naidu, A.K.Rengan* (2022) Herbal biomolecules as nutraceuticals: Herbal Biomolecules in Healthcare Applications, Academic Press

  18. SP Singh, AK Rengan* (2021) Microbial Interactions at Nanobiotechnology Interfaces: Molecular Mechanisms and Applications - Molecular Mechanisms Behind Nano‐Cancer Therapeutics, John Wiley & Sons, Inc.

  19. S.P. Singh, .........A.K. Rengan* (2019) Nanomaterials for Antibiofilm Activity, Introd. to Biofilm Eng. Part 6 - Nanomater. Antibiofilm Act.

Link to updated research articles

google-scholar-png.png

Funding Agencies

iith logo_edited_edited.png
JICA1.jpg
Ukri_Nerc_Logo.jpg
ICMR.jpg
DBT.jpg
Screenshot 2024-04-10 at 3.22.04 PM.png
MoEdu.jpg
Screenshot 2024-04-10 at 3.17.29 PM.png
SERB-LOGO.png
DST1.png
inspire1.jpg
imprint-logo.jpg
Vasudha Foundation.png
z - British Council.jpg
Screenshot 2024-02-05 at 8.49.32 PM.png
newton-bhabha-master-rgb_0.jpg

P-erformance

P-lasmonics

P-atience

P-olysaccharide

P-erseverance

P-eople

P-ersistance

P-ositivity

P-hospholipid

P-olymers

P-roduct

P-value

  • Facebook Social Icon
  • LinkedIn
Site maintained by
Ghanshyam Tilakwar
Last updated on 12/01/2026
 
bottom of page